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RecruitingNCT06950203

The Effect of Supplementation With Fish Oil (EPAX EVOLVE 05) on Sperm Quality

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Trial Parameters

ConditionInfertility, Male
SponsorEpax Norway AS
Study TypeINTERVENTIONAL
PhaseN/A
Enrollment80
SexMALE
Min Age18 Years
Max Age55 Years
Start Date2025-03-10
Completion2026-09-01
Interventions
Very Long Chain Polyunsaturated Fatty AcidsComparator arm (DHA)

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Brief Summary

The study will enrol men that have a poor sperm quality. They will take either a placebo or fish oil capsule (2 per day) for 3 months. At the beginning and end of the study the participant will be asked for a sperm sample for measuring quality parameters.

Eligibility Criteria

Inclusion Criteria: 1. Men aged 18-55 2. Referred for or claiming a semen analysis. 3. Willing to have at least 2 days abstinence of sexual activity prior to a sperm sample being taken. 4. Reduced semen quality defined as: • Progressive motility: \<30% 5. Willing to refrain from omega-3/cod liver oil supplementation during the study. Use of other supplements is allowed. \- Exclusion Criteria: 1. Known allergy to fish products 2. Historically, known, or suspected bacterial infection in reproductive organs 3. Varicocele suspected from physical examination 4. Azoospermia 5. Diagnosis of diabetes (type 2) 6. Diagnosis of Crohn´s Disease 7. Inferior semen quality due to medical reasons, such as cryptorchidism (via questionnaire/medical records) -

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