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Recruiting NCT07002294

NCT07002294 The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial)

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Clinical Trial Summary
NCT ID NCT07002294
Status Recruiting
Phase
Sponsor University of Pittsburgh
Condition Cardiac Arrest (CA)
Study Type INTERVENTIONAL
Enrollment 1,618 participants
Start Date 2026-05-11
Primary Completion 2031-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Transfer to specialty careUsual care

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 1,618 participants in total. It began in 2026-05-11 with a primary completion date of 2031-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This randomized clinical trial will determine if adult participants who are in the emergency department after being resuscitated from a cardiac arrest outside of the hospital benefit from care delivered at specialized centers. The main question that it will answer is whether transferring participants to a hospital with a specialized cardiac arrest service improves recovery of function after 90 days. Participants will receive all usual medical care, but some participants will be offered transfer to a regional cardiac arrest center and others will be offered care at the closest appropriate hospital. Investigators will interview participants after 90 days to assess their recovery.

Eligibility Criteria

Inclusion Criteria: * Out-of-hospital cardiac arrest * Resuscitated from cardiac arrest with palpable pulse in the emergency department * Treated at one of participating hospital emergency departments * Age ≥18 years Exclusion Criteria: * Known prior advanced directives or decision to limit critical care * Known pre-arrest dependent functional status (e.g., living in a skilled nursing facility, hospice or bedbound) * Arrest in the emergency department \>4 hours after arrival * Traumatic etiology of arrest * Known to have opted-out from the SPARC trial

Contact & Investigator

Central Contact

Sara DiFiore-Sprouse

✉ difioresm@upmc.edu

📞 4128642284

Principal Investigator

Jonathan Elmer, MD, MS

PRINCIPAL INVESTIGATOR

University of Pittsburgh

Frequently Asked Questions

Who can join the NCT07002294 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Cardiac Arrest (CA). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07002294 currently recruiting?

Yes, NCT07002294 is actively recruiting participants. Contact the research team at difioresm@upmc.edu for enrollment information.

Where is the NCT07002294 trial being conducted?

This trial is being conducted at Pittsburgh, United States.

Who is sponsoring the NCT07002294 clinical trial?

NCT07002294 is sponsored by University of Pittsburgh. The principal investigator is Jonathan Elmer, MD, MS at University of Pittsburgh. The trial plans to enroll 1,618 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology