Trial Parameters
Brief Summary
The project will carry out the genetic testing of 100000 neonates in the next 5 years. The aim of the project is to construct the Chinese neonatal genome database, establish the genetic testing standard of neonatal genetic diseases, and promote the industrialization of neonatal genetic disease gene testing, improve the training system for genetic counseling.
Eligibility Criteria
Inclusion Criteria: * 1\. Both parents are of Chinese origin; * 2\. Postnatal age less than 28 days; * 3\. Can be retained to at least 1ml venous blood sample; * 4\. Biological parent or guardian's informed consent. Exclusion Criteria: * 1\. the nationality of one of the parents is not the Han nationality or other national minorities; * 2\. reluctance of parents to use genetic sequencing data for subsequent research; * 3\. parents under 18 years of age or incapacitated for decision-making; * 4\. subjects older than 28 days. * 5\. multiple pregnancies; * 6\. lack of access to biological samples from which DNA can be extracted; * 7\. failure to sign informed consent