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Recruiting NCT06268444

Infant Sleep and Exposure to Mixture of Chemical Environmental Pollutants

Trial Parameters

Condition Newborn
Sponsor Centre Hospitalier Universitaire, Amiens
Study Type INTERVENTIONAL
Phase N/A
Enrollment 120
Sex ALL
Min Age N/A
Max Age 6 Months
Start Date 2024-02-07
Completion 2026-02
Interventions
7-day actimetry sleep recordingDetermination of environmental pollutants in breast milkMeasurements of environmental pollutants in indoor air deposited on the bracelet worn by the child

Brief Summary

During their first year of life, children spend more than half their time sleeping, a function essential to their neurodevelopment. This period of maturation and development of the future adult is considered extremely vulnerable to environmental exposure. During this period, the child\'s diet is mainly provided by breastfeeding, where persistent chemical substances have been found. A cocktail of 19 mostly persistent substances (POPs) present in breast milk has recently been identified as the main contributor to neurodevelopmental risk. However, the reality of their impact on neurophysiological development, in particular on infant sleep, has yet to be assessed. In this project, the sleep of children under 6 months of age will be studied using an actimetry watch worn for 7 days by the child, accompanied by a sleep diary. Exposure to environmental pollutants will be assessed by measuring their presence in the infant\'s milk (breastfeeding) and wearing a silicone bracelet to collect air pollutants. A questionnaire on exposure will complement this evaluation.

Eligibility Criteria

Inclusion Criteria: * Infant less than 6 months of age still on milk diet (total) Exclusion Criteria: * Infants with neurological or neurobehavioral disorders * Families who wish to relocate within 7 days of inclusion * Minor parents deprived of their parental rights, not understanding French, in a state of stress, overwhelmed or vulnerable. * Non-affiliation to a social security system

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