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Recruiting NCT05032768

NCT05032768 The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients

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Clinical Trial Summary
NCT ID NCT05032768
Status Recruiting
Phase
Sponsor Fudan University
Condition Radiation Dermatitis
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2021-01-01
Primary Completion 2021-12-31

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age 70 Years
Study Type OBSERVATIONAL
Interventions
post-operative radiotherapy

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2021-01-01 with a primary completion date of 2021-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The breast cancer patients who received radiotherapy after mastectomy and breast reconstruction will be enrolled. The skin microbiome before radiotherapy and its changes after radiotherapy will be analyzed systematically to find out whether the skin microbiome is associated with the severity of radiation dermatitis.

Eligibility Criteria

Inclusion Criteria: 1. Female patients 2. Invasive breast cancer confirmed by pathology 3. Underwent mastectomy and breast reconstruction 4. Radiotherapy after breast reconstruction 5. ECOG score 0-1 6. Signed informed consent Exclusion Criteria: 1. Previous breast or chest radiotherapy 2. Other serious skin diseases (systemic lupus erythematosus, skin sclerosis, et al) and cannot receive radiotherapy 3. Pregnant women 4. Patients who are unwilling or unable to receive regular follow-up.

Contact & Investigator

Central Contact

Wei Shi, MD, Ph.D

✉ wei.shi118@foxmail.com

📞 +86 18121299680

Principal Investigator

Xiaoli Yu, MD, Ph.D

PRINCIPAL INVESTIGATOR

Fudan University

Frequently Asked Questions

Who can join the NCT05032768 clinical trial?

This trial is open to female participants only, aged 18 Years or older, up to 70 Years, studying Radiation Dermatitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05032768 currently recruiting?

Yes, NCT05032768 is actively recruiting participants. Contact the research team at wei.shi118@foxmail.com for enrollment information.

Where is the NCT05032768 trial being conducted?

This trial is being conducted at Shanghai, China.

Who is sponsoring the NCT05032768 clinical trial?

NCT05032768 is sponsored by Fudan University. The principal investigator is Xiaoli Yu, MD, Ph.D at Fudan University. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology