NCT07057817 The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage
| NCT ID | NCT07057817 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Royal College of Surgeons, Ireland |
| Condition | Osteomyelitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2029-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-01-01 with a primary completion date of 2029-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The ACHILLS Trial is a multicentre randomised controlled feasibility study comparing partial calcanectomy with and without the use of an antibiotic-impregnated bone graft substitute (Cerament G) for treating calcaneal osteomyelitis, specifically on wound healing rates, re-infection, and overall efficacy in a sample of 30 patients over a one-year period.
Eligibility Criteria
Inclusion Criteria: * 18 and over * Undergoing partial calcanectomy * Patients with Type1 or Type 2 Diabetes * Patients will be stratified by Pulse status and eGFR Exclusion Criteria: * Patients unfit for surgery * Patients unable to provide informed consent * Patients with overwhelming sepsis that require major amputation * Patients with hypersensitivity to aminoglycosides * Pre-existing calcium metabolism disorder * Severe renal impairment * Patients in whom major limb amputation is deemed inevitable by the treating physician
Contact & Investigator
James Walsh
PRINCIPAL INVESTIGATOR
Beaumont Hospital
Frequently Asked Questions
Who can join the NCT07057817 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Osteomyelitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07057817 currently recruiting?
Yes, NCT07057817 is actively recruiting participants. Contact the research team at james@walshortho.ie for enrollment information.
Where is the NCT07057817 trial being conducted?
This trial is being conducted at Galway, Ireland.
Who is sponsoring the NCT07057817 clinical trial?
NCT07057817 is sponsored by Royal College of Surgeons, Ireland. The principal investigator is James Walsh at Beaumont Hospital. The trial plans to enroll 30 participants.