| NCT ID | NCT05372172 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Vanderbilt University Medical Center |
| Condition | Aging |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,000 participants |
| Start Date | 2021-10-27 |
| Primary Completion | 2030-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,000 participants in total. It began in 2021-10-27 with a primary completion date of 2030-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator studies to develop early detection, prevention, and treatment strategies for Alzheimer's disease. The Clinical Core intends to enroll up to 1000 participants, including individuals who are cognitively unimpaired, have mild cognitive impairment, or have Alzheimer's disease. This cohort of about 1000 participants will be called the Tennessee Alzheimer's Project. Participants will be seen annually for comprehensive clinical characterization and then referred to other studies to enhance Alzheimer's disease research activities.
Eligibility Criteria
Inclusion Criteria: * Age 60 or older * Meet standard criteria for (a) cognitively unimpaired, (b) mild cognitive impairment, or (c) Alzheimer's disease * English speaking * Individuals who lack decisional capacity to provide informed consent at baseline will not be enrolled in the study Exclusion Criteria: * No available reliable study partner (reliable is defined as someone who interacts significantly with the participant and is available to participate in study visits in person or by phone) * History of major psychiatric illness (e.g., schizophrenia, bipolar), neurological illness (e.g., epilepsy, multiple sclerosis, Parkinson's disease), or head injury with significant loss of consciousness. * Unable to undergo MRI (e.g., claustrophobia, ferrous metal in body)
Contact & Investigator
Angela Jefferson, PhD
PRINCIPAL INVESTIGATOR
Professor of Neurology
Frequently Asked Questions
Who can join the NCT05372172 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, studying Aging. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05372172 currently recruiting?
Yes, NCT05372172 is actively recruiting participants. Contact the research team at michelle.houston@vumc.org for enrollment information.
Where is the NCT05372172 trial being conducted?
This trial is being conducted at Nashville, United States.
Who is sponsoring the NCT05372172 clinical trial?
NCT05372172 is sponsored by Vanderbilt University Medical Center. The principal investigator is Angela Jefferson, PhD at Professor of Neurology. The trial plans to enroll 1,000 participants.