NCT04576182 Supportive-Expressive and Emotion-Focused Treatment for Depression
| NCT ID | NCT04576182 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Haifa |
| Condition | Major Depressive Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 124 participants |
| Start Date | 2020-11-29 |
| Primary Completion | 2026-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 124 participants in total. It began in 2020-11-29 with a primary completion date of 2026-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study will explore the mechanisms of change that are activated when individuals receive a treatment that targets their weakness and the mechanisms activated when the treatment capitalize on their strength. Patients will be assigned to one of two types of psychotherapies in treating people with a major depression disorder, expressive-supportive vs. emotion-focused treatment. Their ability to benefit from treatment based on their pre-treatment levels of insight and emotional processing will be examined. This is a four-month protocol, with a 2 year follow up period.
Eligibility Criteria
Inclusion Criteria: * Meeting major depressive disorder diagnostic criteria using the structured clinical interviews for Diagnostic and Statistical Manual of Mental Disorders-5 and scoring more than 14 on the 17-item Hamilton rating scale for depression at two evaluations (one week apart) (Hamilton, 1967). * If on medication, patients' dosage must be stable for at least three months prior to entering the study, and they must be willing to maintain stable dosage for the duration of treatment * Age between 18 and 65 * Hebrew language fluency * Provision of written informed consent. Exclusion Criteria: * Current risk of suicide or self-harm * current substance abuse disorders * current or past schizophrenia or psychosis, bipolar disorder, or severe eating disorder requiring medical monitoring * history of organic mental disease * currently in psychotherapy
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04576182 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Major Depressive Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04576182 currently recruiting?
Yes, NCT04576182 is actively recruiting participants. Contact the research team at sigalzil@gmail.com for enrollment information.
Where is the NCT04576182 trial being conducted?
This trial is being conducted at Haifa, Israel.
Who is sponsoring the NCT04576182 clinical trial?
NCT04576182 is sponsored by University of Haifa. The trial plans to enroll 124 participants.