← Back to Clinical Trials
Recruiting NCT05954702

Supercharged TRAM Evaluation in Cervical Esophagogastroplasty After Esophagectomy

Trial Parameters

Condition Esophagus Cancer
Sponsor Instituto do Cancer do Estado de São Paulo
Study Type INTERVENTIONAL
Phase N/A
Enrollment 60
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-07-21
Completion 2025-07
Interventions
Supercharged TRAM esophagectomyConventional Esophagectomy

Brief Summary

Esophagectomy has high rates of morbidity and mortality, in many cases due to esophagus reconstruction. Anastomotic leakage and fistula are the main esophagectomy complications. Many studies underwent to investigate the cause for anastomotic leakage after esophagectomy, however none of them conclude it is related to surgery or suture technique. However, it seems to be triggered by the ischemia caused after stomach mobilization to esophagus reconstruction, or even tension in the anastomosis. Considering the post esophagectomy with gastroplasty high morbidity and mortality rates, strategies to create a new vascularization source and decrease anastomotic leakage rates is important. In this study researchers will evaluate whether a TRAM flap transfer supercharged is effective on decrease morbidity related to anastomosis ischemia in patients undergoing esophagectomy.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of esophageal malignancy cancer; * Ability to understand and collaborate during treatment; Exclusion Criteria: * Previous gastrectomy; * Previous abdominal surgery with risk of altering stomach vascularization; * Previous head and neck surgery with risk of alteration of cervical vessels.

Related Trials