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Recruiting NCT02972372

Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer

Trial Parameters

Condition Esophagus Cancer
Sponsor The First Affiliated Hospital of Henan University of Science and Technology
Study Type INTERVENTIONAL
Phase N/A
Enrollment 196
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2016-11
Completion 2025-12
Interventions
CRTsurgery

Brief Summary

The aim of this study is to compare outcomes in Chinese patients with locally advanced resectable esophageal squamous cell cancer who have received either surgery or definitive chemoradiation (CRT) by the randomized, open-label, multicenter trial.

Eligibility Criteria

Inclusion Criteria: * Chinese * esophageal squamous cell cancer * mid or lower esophageal cancer * tumor is resectable disease * clinical stage: cT1bN+Mo, or cT2-4aN0-2M0 Exclusion Criteria: * who had distant metastasis to solid visceral organs or local invasion into trachea, descending aorta, or recurrent laryngeal nerve. * who had a serious premorbid condition or a poor physical status that compromised a thoracotomy.

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