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Recruiting NCT05193305

NCT05193305 Study of Healthy Cohort for Early Detection of Cancer

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Clinical Trial Summary
NCT ID NCT05193305
Status Recruiting
Phase —
Sponsor Johns Hopkins University
Condition Healthy
Study Type OBSERVATIONAL
Enrollment 10,000 participants
Start Date 2023-02-01
Primary Completion 2028-02-28

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 10,000 participants in total. It began in 2023-02-01 with a primary completion date of 2028-02-28.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.

Eligibility Criteria

Inclusion Criteria: * All adults 18 years of age of older undergoing upper or lower endoscopy for routine medical care. Exclusion Criteria: * Persons with current malignancy * Persons with history of malignancy and treatment within last 5 years of enrollment, excluding non-melanoma skin cancer or cervical in-situ. * Persons who are unable or unwilling to provide repeat blood samples and complete follow-up questionnaires * Persons who lack the capacity to provide consent * Persons who do not speak English * Persons who are visually or hearing impaired.

Contact & Investigator

Central Contact

Elham Afghani

✉ eafghan1@jhmi.edu

📞 410-955-5000

Principal Investigator

Elham Afghani

PRINCIPAL INVESTIGATOR

Johns Hopkins University

Frequently Asked Questions

Who can join the NCT05193305 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05193305 currently recruiting?

Yes, NCT05193305 is actively recruiting participants. Contact the research team at eafghan1@jhmi.edu for enrollment information.

Where is the NCT05193305 trial being conducted?

This trial is being conducted at Baltimore, United States.

Who is sponsoring the NCT05193305 clinical trial?

NCT05193305 is sponsored by Johns Hopkins University. The principal investigator is Elham Afghani at Johns Hopkins University. The trial plans to enroll 10,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology