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Recruiting NCT05193305

Study of Healthy Cohort for Early Detection of Cancer

Trial Parameters

Condition Healthy
Sponsor Johns Hopkins University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 10,000
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-02-01
Completion 2028-02-28

Brief Summary

Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.

Eligibility Criteria

Inclusion Criteria: * All adults 18 years of age of older undergoing upper or lower endoscopy for routine medical care. Exclusion Criteria: * Persons with current malignancy * Persons with history of malignancy and treatment within last 5 years of enrollment, excluding non-melanoma skin cancer or cervical in-situ. * Persons who are unable or unwilling to provide repeat blood samples and complete follow-up questionnaires * Persons who lack the capacity to provide consent * Persons who do not speak English * Persons who are visually or hearing impaired.

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