NCT06180603 Strategy for Prompt and Effective Thoracentesis in the Emergency Department
| NCT ID | NCT06180603 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Aarhus |
| Condition | Pleural Effusion |
| Study Type | INTERVENTIONAL |
| Enrollment | 188 participants |
| Start Date | 2024-01-15 |
| Primary Completion | 2025-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 188 participants in total. It began in 2024-01-15 with a primary completion date of 2025-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The SPEEDTAP-trial is a prospective, randomised, investigator-initiated, multicenter, clinical superior trial investigating two thoracentesis methods in four emergency departments (ED) in Central Denmark Region. Patients are randomised to either manual fluid removal in the ED or passively fluid drainage using gravity in the radiology department (standard of care). Primary outcome: time from clinical indication to complete drainage and 188 patients will be included. Key secondary outcomes include length of stay, ED admission to ED discharge and safety end-points.
Eligibility Criteria
Inclusion Criteria: * Patients ≥ 18 years admitted to the ED * Pleural effusion detected by any imaging modality (e.g., bedside ultrasound, chest x-ray, computed tomography) * Clinically justified need for thoracentesis ( symptomatic relief and/or define the etiology of the effusion * Without contraindication for thoracentesis in the emergency department (e.g., anticoagulant treatment) Exclusion Criteria: * Life-threatening respiratory distress * Not able to give consent * Previous pleurodesis * Effusion does not appear free-flowing due to septations or loculations / suspected empyema * Prior enrollment in the trial * If randomization is not possible because decision to insert a pigtail catheter is made in the radiology department
Contact & Investigator
Sandra T Langsted
PRINCIPAL INVESTIGATOR
Aarhus University Hospital
Frequently Asked Questions
Who can join the NCT06180603 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Pleural Effusion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06180603 currently recruiting?
Yes, NCT06180603 is actively recruiting participants. Contact the research team at sandra.langsted@clin.au.dk for enrollment information.
Where is the NCT06180603 trial being conducted?
This trial is being conducted at Aarhus, Denmark, Gødstrup, Denmark, Horsens, Denmark, Randers, Denmark and 2 additional locations.
Who is sponsoring the NCT06180603 clinical trial?
NCT06180603 is sponsored by University of Aarhus. The principal investigator is Sandra T Langsted at Aarhus University Hospital. The trial plans to enroll 188 participants.