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Recruiting Phase 4 NCT06523465

NCT06523465 Statin Combined with Amlodipine Treats Primary Aldosteronism

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Clinical Trial Summary
NCT ID NCT06523465
Status Recruiting
Phase Phase 4
Sponsor Third Military Medical University
Condition Primary Aldosteronism
Study Type INTERVENTIONAL
Enrollment 180 participants
Start Date 2024-09-10
Primary Completion 2025-12-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
Simvastatin combined with Amlodipine besylateSimvastatin combined with Spironolactone and Amlodipine besylate.Amlodipine besylate combined Spironolactone

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 180 participants in total. It began in 2024-09-10 with a primary completion date of 2025-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The drug treatment for primary aldosteronism (PA) is limited and difficult to improve long-term cardiovascular outcomes. This study plans to enroll patients with primary aldosteronism and randomly divide into 3 groups: scheme 1: Statin combined with amlodipine besylate, scheme 2: Statin combined with Spironolactone and Amlodipine besylate. scheme 3: Amlodipine besylate combined with Spironolactone , to observe the changes in plasma aldosterone level, 24-hour urinary aldosterone, blood pressure, and long-term cardiovascular risk.

Eligibility Criteria

Inclusion Criteria: * Clinical diagnosis of primary aldosteronism Exclusion Criteria: * Allergy to drugs in this study * Pregnancy * Severe liver and kidney dysfunction * Mental illness

Contact & Investigator

Central Contact

sun fang

✉ sun_fang2007@163.com

📞 +862368729587

Frequently Asked Questions

Who can join the NCT06523465 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Primary Aldosteronism. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06523465 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT06523465 currently recruiting?

Yes, NCT06523465 is actively recruiting participants. Contact the research team at sun_fang2007@163.com for enrollment information.

Where is the NCT06523465 trial being conducted?

This trial is being conducted at Chongqing, China.

Who is sponsoring the NCT06523465 clinical trial?

NCT06523465 is sponsored by Third Military Medical University. The trial plans to enroll 180 participants.

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