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Recruiting NCT06053320

NCT06053320 Spatial-Motor Stroke-Rehab Study

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Clinical Trial Summary
NCT ID NCT06053320
Status Recruiting
Phase
Sponsor Emory University
Condition Spatial Neglect
Study Type INTERVENTIONAL
Enrollment 65 participants
Start Date 2023-04-11
Primary Completion 2026-09

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 90 Years
Study Type INTERVENTIONAL
Interventions
Prism adaptation therapy (PAT) + Electrical stimulation (E-stim)Prism adaptation therapy (PAT) + Sham StimulatorGait Training

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 65 participants in total. It began in 2023-04-11 with a primary completion date of 2026-09.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.

Eligibility Criteria

Inclusion Criteria: Young Adults Able Bodied (YAB) Individuals * 18-30 years * Able-Bodied (healthy without any physical disability or neurological disorder) Older Adults Able-Bodied Individuals (OAB) * 45-90 years * Able-Bodied (healthy without any physical disability or neurological disorder) Individuals with right hemisphere stroke (40-90 years) * \>3 months following stroke. * Presence of Aiming SN * Ability to walk \>10m with or without assistive devices. * Unilateral left-sided hemiparesis with gross arm strength of ≤ grade 4/5 on the Medical Research Council Scale * Ability to follow 3-stage commands and provide informed consent. Exclusion Criteria: Young Adults Able-Bodied (YAB) Individuals and Older Adults Able-Bodied Individuals (OAB) * History or evidence of orthopedic or physical disability * History or evidence of neurological pathology * Pregnancy (female) * Uncontrolled hypertension * Cardiac pacemaker or other implanted electronic system * Presence of skin conditions preventing the electrical stimulation setup * Impaired sensation in the left upper limb. * Bruises or cuts at the stimulation electrode placement site * Concurrent enrollment in rehabilitation or another investigational study. * History or evidence of orthopedic or physical disability interfering with study procedures * History or evidence of neurological pathology or disorder * Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) that may interfere with study procedures * Contraindications to TMS, such as metal implants, medications that can increase cortical excitability, and unexplained dizziness in the past 6 months Individuals with right hemisphere stroke (40-90 years) * History or brainstem strokes * Cerebellar disorders * Impaired sensation in the left upper limb. * History of other neurological disorders * Uncontrolled hypertension * Cardiac pacemaker or other implanted electronic system * Pregnancy (female) * Presence of skin condition * Bruises at the electrode placement site * Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) or other medical conditions that can interfere with study procedures * Contraindications to TMS, such as metal implants in the brain, medications that will increase cortical excitability, etc.

Contact & Investigator

Central Contact

Fisayo Aloba, PT, DPT

✉ olufisayo.aloba@emory.edu

📞 404-712-5803

Principal Investigator

Trisha Kesar, PT, PhD

PRINCIPAL INVESTIGATOR

Emory University

Frequently Asked Questions

Who can join the NCT06053320 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Spatial Neglect. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06053320 currently recruiting?

Yes, NCT06053320 is actively recruiting participants. Contact the research team at olufisayo.aloba@emory.edu for enrollment information.

Where is the NCT06053320 trial being conducted?

This trial is being conducted at Atlanta, United States, Atlanta, United States, Atlanta, United States.

Who is sponsoring the NCT06053320 clinical trial?

NCT06053320 is sponsored by Emory University. The principal investigator is Trisha Kesar, PT, PhD at Emory University. The trial plans to enroll 65 participants.

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