NCT05367297 South Asians and Coronary Plaque Registry
| NCT ID | NCT05367297 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Texas Southwestern Medical Center |
| Condition | Coronary Artery Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2022-06-15 |
| Primary Completion | 2027-04-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2022-06-15 with a primary completion date of 2027-04-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.
Eligibility Criteria
Inclusion Criteria: * Males and Females: Age 18 years or above * South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh) * We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers) * Sampling Method: Probability Sample Exclusion Criteria: * Under the age of 18 years * Unable to give informed consent * Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min * Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker * Body mass index (BMI) of 35 or greater * Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast * Anyone who cannot do CCTA for any reason * Pregnancy
Contact & Investigator
Anand Rohatgi, MD
PRINCIPAL INVESTIGATOR
University of Texas Southwestern Medical Center
Frequently Asked Questions
Who can join the NCT05367297 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Coronary Artery Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05367297 currently recruiting?
Yes, NCT05367297 is actively recruiting participants. Contact the research team at SAHealth@UTSouthwestern.edu for enrollment information.
Where is the NCT05367297 trial being conducted?
This trial is being conducted at Dallas, United States.
Who is sponsoring the NCT05367297 clinical trial?
NCT05367297 is sponsored by University of Texas Southwestern Medical Center. The principal investigator is Anand Rohatgi, MD at University of Texas Southwestern Medical Center. The trial plans to enroll 300 participants.