NCT06886477 Sickle Cell, Pain and Mediterranean Diet
| NCT ID | NCT06886477 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Illinois at Chicago |
| Condition | Sickle Cell |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-05-01 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-05-01 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.
Eligibility Criteria
Inclusion Criteria: * Sickle Cell Disease Diagnosis * Chronic non-vaso-occlusive pain experienced on average ≥ 3 days per week for \> 6 months (based on a response of "Most days," "Every day," or "Some days" and not "Never" to the question "In the past 6 months, how often have you had pain?") * Ability to speak, read, write, and understand English * A Mediterranean Eating Pattern for Americans (MEPA-III) score \<13, indicating that they do not follow a Mediterranean diet. Exclusion Criteria: * Having taken systemic antimicrobials (to treat an infection in the previous 4 weeks) * History of colon cancer or inflammatory bowel disease (given potential untoward effects on the gut microbiome) * History of Clostridium difficile infection in the preceding 12 weeks; (4) unable to agree to maintain physical activity at the current level for the duration of the study * Currently following a Mediterranean diet, vegan diet, or dietary restrictions (e.g., religious, food intolerance/allergy) that preclude adoption of a Mediterranean diet * Lack of access to a space to safely store and reheat food items * Living in a facility that provides meals. * Pregnancy or breastfeeding * More than 7 in-patient hospital stays in the last year * Currently receiving dialysis treatment
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06886477 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Sickle Cell. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06886477 currently recruiting?
Yes, NCT06886477 is actively recruiting participants. Contact the research team at tussing@uic.edu for enrollment information.
Where is the NCT06886477 trial being conducted?
This trial is being conducted at Chicago, United States.
Who is sponsoring the NCT06886477 clinical trial?
NCT06886477 is sponsored by University of Illinois at Chicago. The trial plans to enroll 30 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.