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Recruiting NCT04957537

NCT04957537 Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia

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Clinical Trial Summary
NCT ID NCT04957537
Status Recruiting
Phase
Sponsor University Hospital, Toulouse
Condition Primary Progressive Aphasia
Study Type INTERVENTIONAL
Enrollment 15 participants
Start Date 2021-09-20
Primary Completion 2025-09

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 100 Years
Study Type INTERVENTIONAL
Interventions
semantic therapy and semantic re-education

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 15 participants in total. It began in 2021-09-20 with a primary completion date of 2025-09.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This project aims to measure the effect of a semantic rehabilitation protocol for patients with primary progressive semantic aphasia and using the SCED methodology.

Eligibility Criteria

Inclusion Criteria: * Have a diagnosis of primary progressive semantic aphasia according to the criteria of Gorno-Tempini et al (2011) (Appendix A) * Being in the mild to moderate stage of dementia (MMSE score between 10 and 28) (Crum et al., 1993; Derouesné et al., 1999) * Common French * Being affiliated to a social security scheme * Being over the age of 18 years old Exclusion Criteria: * Have significant uncorrected visual and/or hearing impairment * Have a history of brain injuries, major head trauma * Have untreated psychiatric disorders * Have significant motor and/or comprehension problems that make it impossible to take part in the study * Chronical use of drugs and/or alcohol * Under guardians or curators * Severe depression (Beck's depression scale score \> 9) (Beck \& al., 1961)

Contact & Investigator

Central Contact

Jérémie PARIENTE, MD PhD

✉ pariente.j@chu-toulouse.fr

📞 0561777686

Principal Investigator

Jérémie PARIENTE, MD PhD

PRINCIPAL INVESTIGATOR

University Hospital, Toulouse

Frequently Asked Questions

Who can join the NCT04957537 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Primary Progressive Aphasia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04957537 currently recruiting?

Yes, NCT04957537 is actively recruiting participants. Contact the research team at pariente.j@chu-toulouse.fr for enrollment information.

Where is the NCT04957537 trial being conducted?

This trial is being conducted at Toulouse, France.

Who is sponsoring the NCT04957537 clinical trial?

NCT04957537 is sponsored by University Hospital, Toulouse. The principal investigator is Jérémie PARIENTE, MD PhD at University Hospital, Toulouse. The trial plans to enroll 15 participants.

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