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Medical Condition

primary progressive aphasia

Total Trials
6
Recruiting Now
6
Trial Phases
Phase 2, Phase 4

ClinicalMetric tracks all active clinical trials for primary progressive aphasia sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — primary progressive aphasia Clinical Trials

How many clinical trials are currently recruiting for primary progressive aphasia?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for primary progressive aphasia, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for primary progressive aphasia?
primary progressive aphasia research spans Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a primary progressive aphasia clinical trial?
Eligibility criteria for primary progressive aphasia trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
1
Phase 4
1
Top Sponsors
Northwestern University 1 trial
Simon Ducharme, MD 1 trial
Medical College of Wisconsin 1 trial
Mayo Clinic 1 trial
IRCCS Centro San Giovanni di Dio Fatebenefratelli 1 trial

Recruiting Clinical Trials

NCT00537004
Recruiting
Language in Primary Progressive Aphasia
Enrollment
500 pts
Location
United States
Sponsor
Northwestern University
View Trial →
NCT05742698 Phase 2
Recruiting
Nabilone for Agitation in Frontotemporal Dementia
Enrollment
45 pts
Location
Canada
Sponsor
Simon Ducharme, MD
View Trial →
NCT07650188
Recruiting
Stimulating the Aging Brain Using Brain and Sensory Stimulation
Enrollment
20 pts
Location
United States
Sponsor
Medical College of Wisconsin
View Trial →
NCT01818661 Phase 4
Recruiting
Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech
Enrollment
50 pts
Location
United States
Sponsor
Mayo Clinic
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NCT05730023
Recruiting
A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:3430931
Enrollment
60 pts
Location
Italy
Sponsor
IRCCS Centro San Giovanni di D...
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NCT03887481
Recruiting
Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA
Enrollment
60 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →

Related Conditions

ppa (2) frontotemporal dementia (1) frontotemporal dementia behavioral variant (1) bvftd (1) ftd (1) non fluent aphasia (1) apraxia of speech (1) primary progressive non fluent aphasia (1) logopenic progressive aphasia (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology