NCT07451613 Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease
| NCT ID | NCT07451613 |
| Status | Recruiting |
| Phase | Phase 1, Phase 2 |
| Sponsor | Leslie Thompson |
| Condition | Huntington Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 21 participants |
| Start Date | 2026-04-06 |
| Primary Completion | 2028-06 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.
Eligibility Criteria
Please note this may not be a complete list of eligibility criteria. Inclusion Criteria: * Have decision-making capacity and be able to provide written informed consent. * Are between 18 to 65 years of age * Have genetically confirmed diagnosis of Huntington's Disease * Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture. Exclusion Criteria: * Are pregnant * Test positive for human immunodeficiency virus (HIV), hepatitis C or chronic hepatitis B at Screening * Have an implanted deep brain stimulation device.