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Recruiting NCT06556121

NCT06556121 Saddle Block With IT Morphine for Penile Inversion Vaginoplasty

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Clinical Trial Summary
NCT ID NCT06556121
Status Recruiting
Phase
Sponsor Women's College Hospital
Condition Pain, Postoperative
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2025-08-07
Primary Completion 2026-12

Eligibility & Interventions

Sex Male only
Min Age 18 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
Saddle blockpudendal nerve block

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2025-08-07 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Penile Inversion Vaginoplasty (PIV) is a transition-related surgery (TRS) that is associated with severe postoperative pain. The optimal pain management strategies for this surgery remain unknown. We hypothesized that the addition of a saddle block with intrathecal morphine would yield clinically important analgesic benefits.

Eligibility Criteria

Inclusion Criteria: * ASA I-III patients * Ages 18-70 years * Penile Inversion Vaginoplasty Exclusion Criteria: * Local infection * History of use of over 30mg oxycodone or equivalent per day. * Contraindication to a component of multi-modal analgesia * Complications or adverse events unrelated to the local anesthetic that precludes evaluation of the primary and secondary outcome measures. * Unable to speak or read English. * Revision and Vulvaplasty surgeries

Contact & Investigator

Central Contact

Didem Bozak

✉ didem.bozak@wchospital.ca

📞 416-323-6008

Principal Investigator

Richard Brull, MD

PRINCIPAL INVESTIGATOR

Women's College Hospital

Frequently Asked Questions

Who can join the NCT06556121 clinical trial?

This trial is open to male participants only, aged 18 Years or older, up to 70 Years, studying Pain, Postoperative. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06556121 currently recruiting?

Yes, NCT06556121 is actively recruiting participants. Contact the research team at didem.bozak@wchospital.ca for enrollment information.

Where is the NCT06556121 trial being conducted?

This trial is being conducted at Toronto, Canada.

Who is sponsoring the NCT06556121 clinical trial?

NCT06556121 is sponsored by Women's College Hospital. The principal investigator is Richard Brull, MD at Women's College Hospital. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology