NCT06128746 rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT
| NCT ID | NCT06128746 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The University of Hong Kong |
| Condition | CP (Cerebral Palsy) |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2024-01-13 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2024-01-13 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This RCT aims to investigate the effect of repetitive transcranial magnatic stimulation (rTMS) in treating children with hemiplegoc cerebral palsy. The study will measure any improvement in spasticity after using contra-lesional inhibitory rTMS follow by intensive limb training. Participants will attend a 10-day rTMS treatment sessions, follow by intensive training of the impaired limb. They will also undergo MRI scans before and after the treatment to investiagte the underlying neurophysiological mechanisms that lead to changes clinically by using TMS as well as MR-DKI. Researchers will compare the intervention group and the sham group to see if rTMS could result in improvement of participants' spasticity.
Eligibility Criteria
Inclusion Criteria: * Patients aged between 7 years and 18 years * Diagnosis of cerebral palsy with hemiplegia * Upper limb spasticity ≥ 1 * IQ ≥ 50 Exclusion Criteria: * Any contra-indications to rTMS * Severe spasticity (score of 4 or more in Ashworth scale) * Uncontrollable epilepsy * History of Botulinum toxin A injection in previous 6 months * Upper limb casting in previous 6 months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06128746 clinical trial?
This trial is open to participants of all sexes, aged 7 Years or older, up to 18 Years, studying CP (Cerebral Palsy). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06128746 currently recruiting?
Yes, NCT06128746 is actively recruiting participants. Contact the research team at wytso@hku.hk for enrollment information.
Where is the NCT06128746 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT06128746 clinical trial?
NCT06128746 is sponsored by The University of Hong Kong. The trial plans to enroll 20 participants.
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