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Recruiting NCT06841471

NCT06841471 Role of Corneal Nerves in Dry Eye Disease

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Clinical Trial Summary
NCT ID NCT06841471
Status Recruiting
Phase
Sponsor Daniela Nosch
Condition Dry Eye Disease (DED)
Study Type OBSERVATIONAL
Enrollment 140 participants
Start Date 2025-02-20
Primary Completion 2025-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 140 participants in total. It began in 2025-02-20 with a primary completion date of 2025-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss. Additionally, it seeks to investigate whether these factors vary based on the severity of dry eye symptoms.

Eligibility Criteria

Inclusion Criteria: * Group with DED: Diagnosis of DED based on the TFOS DEWS II report * Group without DED: No diagnosis of DED Exclusion Criteria: * Exclusion criteria: * Systemic disease that may affect ocular health and innervation * injury or history of operations on the anterior or posterior segment of the eye, which can affect the corneal structure and physiology * regular application of systemic or ocular medication known to affect the tear film except from DED medications * eye drops or makeup on the day of measurement. Remarks: Contact lens wearers are asked not to wear contact lenses for 1 week before the first appointment. Participant with DED medications will be asked to use only conservative-free eye drops on the days of examination

Contact & Investigator

Central Contact

Daniela S Nosch, BSc MSc PhD

✉ daniela.nosch@fhnw.ch

📞 41629572603

Frequently Asked Questions

Who can join the NCT06841471 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Dry Eye Disease (DED). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06841471 currently recruiting?

Yes, NCT06841471 is actively recruiting participants. Contact the research team at daniela.nosch@fhnw.ch for enrollment information.

Where is the NCT06841471 trial being conducted?

This trial is being conducted at Olten, Switzerland.

Who is sponsoring the NCT06841471 clinical trial?

NCT06841471 is sponsored by Daniela Nosch. The trial plans to enroll 140 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology