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dry eye

Total Trials
8
Recruiting Now
8
Trial Phases
Phase 2, Phase 4

ClinicalMetric tracks all active clinical trials for dry eye sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — dry eye Clinical Trials

How many clinical trials are currently recruiting for dry eye?
ClinicalMetric currently tracks 8 actively recruiting clinical trials for dry eye, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for dry eye?
dry eye research spans Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a dry eye clinical trial?
Eligibility criteria for dry eye trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
1
Phase 4
1
Top Sponsors
Neuro-Ophthalmology of Texas 1 trial
IRCCS Azienda Ospedaliero-Universitaria di Bologna 1 trial
Louis Tong 1 trial
Indiana University 1 trial
Vanda Pharmaceuticals 1 trial

Recruiting Clinical Trials

NCT07566975
Recruiting
Real-World Assessment of VEVYE® for Short-Term Symptom and Sign Improvement of Dry Eye Disease in a Neuro-Ophthalmology Clinic: A 6-Month Prospective Observational Study
Enrollment
50 pts
Location
United States
Sponsor
Neuro-Ophthalmology of Texas
View Trial →
NCT06830551
Recruiting
The Effect of Cord Blood Serum Eyes Drops Administer in Patients With Severe Keratopathy Related to EGFR-I Treatment
Enrollment
10 pts
Location
Italy
Sponsor
IRCCS Azienda Ospedaliero-Univ...
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NCT07323264
Recruiting
SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery
Enrollment
110 pts
Location
Singapore
Sponsor
Louis Tong
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NCT07579130
Recruiting
Comparative Assessment of Lipid Layer Thickness Measurements
Enrollment
50 pts
Location
United States
Sponsor
Indiana University
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NCT07179055 Phase 2
Recruiting
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
Enrollment
160 pts
Location
United States
Sponsor
Vanda Pharmaceuticals
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NCT07297849
Recruiting
Eyelid Closure in Keratometry
Enrollment
29 pts
Location
Austria
Sponsor
Vienna Institute for Research ...
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NCT06841471
Recruiting
Role of Corneal Nerves in Dry Eye Disease
Enrollment
140 pts
Location
Switzerland
Sponsor
Daniela Nosch
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NCT07266948 Phase 4
Recruiting
Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work
Enrollment
40 pts
Location
United States
Sponsor
Southern College of Optometry
View Trial →

Related Conditions

ocular surface disease (1) dry eye disease ded (1) dry eye sensation (1) corneal nerve (1) eye diseases (1) eyes dry chronic (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology