Role of Candidate Proteins in Capillary Leakage During Acute Circulatory Failure
Trial Parameters
Brief Summary
* Testing the association between circulating candidate proteins and the level of vascular leakage for three distinct forms of circulatory failure: cardiogenic shock, septic shock, and post-resuscitation syndrome. * Describing immuno-inflammatory profiles associated with massive vascular leakage during those three forms of circulatory failure in humans
Eligibility Criteria
Inclusion Criteria: 1. Informed consent from patient or a legal representative/family member/close relative. The patient will be asked to give his/her consent for the continuation of the trial when his/her condition will allow. 2. Affiliation to social security (AME excluded) 3. Patient with one of the circulatory failures described below: * septic shock * cardiogenic shock * post-resuscitation syndrome * Cardiogenic shock: * Need for a catecholamine support to maintain mean arterial pressure\>65 mmHg, AND * Cardiac index \<2 L/min/m2 or left ventricular ejection fraction (LVEF)\<35%, AND * Lactate \>2.0 mmol/l * Post-resuscitation syndrome: * Cardiac arrest (absence of spontaneous respiration, palpable heartbeat, and responsiveness to stimuli\> 1 min) with a compatible electrocardiogram (asystole/pulseless electrical activity/ventricular tachycardia), AND * Need for a catecholamine support to maintain mean arterial pressure\>65 mmHg, AND * Lactate \>2.0 mmol/l * Septic shock: * Suspec