Medical Condition

septic shock

Total Trials

13

Recruiting Now

13

Trial Phases

Phase 2, Phase 3, Phase 2, Phase 4

ClinicalMetric tracks all active clinical trials for septic shock sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — septic shock Clinical Trials

How many clinical trials are currently recruiting for septic shock?

ClinicalMetric currently tracks 13 actively recruiting clinical trials for septic shock, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 13. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for septic shock?

septic shock research spans Phase 2 (3 trials), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a septic shock clinical trial?

Eligibility criteria for septic shock trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

Phase 3

Phase 4

Top Sponsors

Pauls Stradins Clinical University Hospital 1 trial

Nantes University Hospital 1 trial

Hannover Medical School 1 trial

Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva 1 trial

Centre Hospitalier Universitaire, Amiens 1 trial

Recruiting Clinical Trials

NCT07419802

Recruiting

OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study

Pauls Stradins Clinical Univer...

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NCT06754696

Recruiting

Evaluation of Blood Protein O-GlcNAcylation Levels in Children

Nantes University Hospital

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NCT05726825

Recruiting

Efficacy of Add-on Plasma Exchange As an Adjunctive Strategy Against Septic Shock

Enrollment

274 pts

Location

Austria, Germany, Sw...

Sponsor

Hannover Medical School

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NCT07264543 Phase 2, Phase 3

Recruiting

Early Methylene Blue in the Microhemodynamics of Septic Patients

Centro de Estudos e Pesquisa e...

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NCT07354568

Recruiting

Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock

Centre Hospitalier Universitai...

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NCT06481410

Recruiting

Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock

First Affiliated Hospital of Z...

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NCT07273526

Recruiting

Adrenaline V/s Dopamine in Fuid Refractory Septic Shock

Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study

University Hospital, Angers

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NCT05349370

Recruiting

Lactate Kinetics in Septic Shock

Karolinska University Hospital

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NCT03334006 Phase 2

Recruiting

Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis

RWTH Aachen University

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NCT07716956

Recruiting

Effect of Targeting Upper Normal Serum Magnesium Levels on Norepinephrine Requirements in Septic Shock Patients

Alexandria University

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NCT06670963 Phase 4

Recruiting

Use of Epoetin Alfa and Iron Derisomaltose in Treatment of Anemia in Patients With Sepsis or Septic Shock: a Randomized Controlled Trial

Therapeutic Plasma Exchange in Septic Shock: A Pilot Study

University of Manitoba

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Related Conditions

sepsis (7) blood purification (1) hemoadsorption (1) development and health (1) metabolism changes (1) hypoperfusion (1) cardiogenic shock acute (1) bypass cardiopulmonary (1) mechanical circulatory support (1) myocardial infarction mi (1) cardiogenic shock post myocardial infarction (1) methylene blue (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology