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Recruiting NCT04652180

NCT04652180 Robot-assisted Thoracic Approach Versus Open Transthoracic Esophagectomy .

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Clinical Trial Summary
NCT ID NCT04652180
Status Recruiting
Phase
Sponsor Hospital Universitari de Bellvitge
Condition Esophageal Cancer
Study Type INTERVENTIONAL
Enrollment 108 participants
Start Date 2020-11-06
Primary Completion 2025-12-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Esophagectomy

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 108 participants in total. It began in 2020-11-06 with a primary completion date of 2025-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a randomized controlled trial designed to compare robot-assisted thoracic approach with open transthoracic esophagectomy (Ivor Lewis technique) as a surgical treatment for resectable esophageal cancer. If our hypothesis is proved correct, robot-assisted thoracic approach will result in a lower percentage of respiratory and overall postoperative complications, lower blood loss, shorter hospital stay, but with at least similar oncologic outcomes and better postoperative quality of life compared with the open transthoracic esophagectomy (current standard).

Eligibility Criteria

Inclusion Criteria: * Age ≥18 years. * Histologically proven adenocarcinoma, squamous cell carcinoma, undifferentiated carcinoma or carcinoma of the gastro-esophageal junction (GEJ) Siewert I or II. * Surgical resectable (T1-4a, N0-3, M0). * Childbearing potential women (period between menarche and menopause), pregnancy negative test is mandatory. * Written informed consent. Exclusion Criteria: * Stage IV or GEJ Siewert III esophageal cancer. * Contraindication of transthoracic esophagectomy in two fields. * Pre- or concomitant cancer or conditions which interferes with the study (e.g. prior thoracic surgery or trauma. Rationale: these patients may undergo open resection).

Contact & Investigator

Central Contact

Natàlia Cornellà, Surgeon

✉ nataliacornellagcirurgia@gmail.com

📞 +34645976556

Principal Investigator

Leandre Farran, PhD Surgeon

STUDY DIRECTOR

Frequently Asked Questions

Who can join the NCT04652180 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Esophageal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04652180 currently recruiting?

Yes, NCT04652180 is actively recruiting participants. Contact the research team at nataliacornellagcirurgia@gmail.com for enrollment information.

Where is the NCT04652180 trial being conducted?

This trial is being conducted at L'Hospitalet de Llobregat, Spain.

Who is sponsoring the NCT04652180 clinical trial?

NCT04652180 is sponsored by Hospital Universitari de Bellvitge. The principal investigator is Leandre Farran, PhD Surgeon. The trial plans to enroll 108 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology