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Recruiting NCT07638462

NCT07638462 RIsE Stroke Mobility Study

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Clinical Trial Summary
NCT ID NCT07638462
Status Recruiting
Phase
Sponsor Wake Forest University Health Sciences
Condition Acute Ischemic Stroke
Study Type INTERVENTIONAL
Enrollment 50 participants
Start Date 2026-07-08
Primary Completion 2027-04

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
activPAL device

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 50 participants in total. It began in 2026-07-08 with a primary completion date of 2027-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is designed to better understand how patients with severe stroke move during their hospital stay. It will track their activity using a small wearable device (activPAL) along with standard mobility information already collected in clinical care. The goal is to learn what typical movement patterns look like early after a stroke and how well patients meet mobility goals while in the hospital. What is learned from this study may allow determination of how treatment for stroke patients may be improved to improve patient long-term mobility.

Eligibility Criteria

Inclusion Criteria: * Adults aged 18 years and older * Hospitalized patients with acute ischemic stroke * Initial National Institutes of Health Stroke Scale (NIHSS) score of 10 or greater * Baseline modified Rankin Scale (mRS) score of 0-2 * Current modified Rankin Scale (mRS) score of 3-5 Exclusion Criteria: * Current or expected End-of-life discussions * Current plans for surgical intervention * Patients with pre-mRS of 3-5 * Patients with orthopedic, musculoskeletal, integumentary injury that would prevent safe weight bearing, mobility or equipment use * Uncontrolled cardiorespiratory dysfunction or disease * Active/uncontrolled seizures * Isolation status that would prevent mobility outside of the room * Weight that exceeds the safe limits of mobility equipment

Contact & Investigator

Central Contact

Jeremy Rhoten, MHA, RN

✉ Jeremy.Rhoten@advocatehealth.org

📞 704-355-7403

Principal Investigator

Rahul Karamchandani, MD

PRINCIPAL INVESTIGATOR

Wake Forest University Health Sciences

Frequently Asked Questions

Who can join the NCT07638462 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Ischemic Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07638462 currently recruiting?

Yes, NCT07638462 is actively recruiting participants. Contact the research team at Jeremy.Rhoten@advocatehealth.org for enrollment information.

Where is the NCT07638462 trial being conducted?

This trial is being conducted at Winston-Salem, United States.

Who is sponsoring the NCT07638462 clinical trial?

NCT07638462 is sponsored by Wake Forest University Health Sciences. The principal investigator is Rahul Karamchandani, MD at Wake Forest University Health Sciences. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology