NCT07241949 Regional Analgesia Techniques for Laparoscopic Cholecystectomy
| NCT ID | NCT07241949 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cukurova University |
| Condition | Postoperative Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 147 participants |
| Start Date | 2025-12-01 |
| Primary Completion | 2026-11-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 147 participants in total. It began in 2025-12-01 with a primary completion date of 2026-11-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on postoperative pain and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The primary endpoint is total tramadol consumption within 24 hours postoperatively. Secondary outcomes include pain scores, additional analgesic use, incidence of nausea/vomiting, mobilization time, and length of hospital stay.
Eligibility Criteria
Inclusion Criteria: * Age between 18 and 65 years * Scheduled for elective laparoscopic cholecystectomy under general anesthesia * ASA physical status I-III * Able to understand the study procedure and provide informed consent Exclusion Criteria: Patient refusal or inability to provide informed consent Allergy or contraindication to local anesthetics, tramadol, or study medications Coagulopathy or current anticoagulant therapy Local infection at the planned block injection site Severe hepatic or renal impairment Chronic opioid use or opioid dependence Neurological or psychiatric disorders affecting pain perception or communication Pregnancy or breastfeeding Body mass index (BMI) \> 35 kg/m² Conversion to open cholecystectomy during surgery
Contact & Investigator
Nurefsan Sadikoglu, MD
PRINCIPAL INVESTIGATOR
Cukurova University Hospital
Frequently Asked Questions
Who can join the NCT07241949 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07241949 currently recruiting?
Yes, NCT07241949 is actively recruiting participants. Contact the research team at nurefsansadikoglu@gmail.com for enrollment information.
Where is the NCT07241949 trial being conducted?
This trial is being conducted at Adana, Turkey (Türkiye).
Who is sponsoring the NCT07241949 clinical trial?
NCT07241949 is sponsored by Cukurova University. The principal investigator is Nurefsan Sadikoglu, MD at Cukurova University Hospital. The trial plans to enroll 147 participants.