NCT06457828 Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
| NCT ID | NCT06457828 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Suez Canal University |
| Condition | Postoperative Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2021-02-01 |
| Primary Completion | 2024-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2021-02-01 with a primary completion date of 2024-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth. The main question it aims to answer is: • How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not. Researchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.
Eligibility Criteria
Inclusion Criteria: * Symptomatic acute irreversible pulpitis in molar teeth. * Normal periapical condition including periapical radiography with minimal widening of periodontal ligament. * Normal probing depth. * No medical condition. * No contraindication for administration of corticosteroids and local anesthesia. Exclusion Criteria: * Facial or oral paresthesia. * Pregnancy \& breastfeeding. * Unrestorable tooth. * Marginal periodontal disease. * Presence of a crown on the tooth involved. * Over instrumentation during root canal treatment. * Long-term use of corticosteroids. * False-positive cases of sensibility test with necrosis discovered after gaining access to the tooth. * Cases requiring intrapulpal injection to promote anesthesia.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06457828 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 60 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06457828 currently recruiting?
Yes, NCT06457828 is actively recruiting participants. Contact the research team at sultan_mustafa@hotmail.com for enrollment information.
Where is the NCT06457828 trial being conducted?
This trial is being conducted at Ismailia, Egypt.
Who is sponsoring the NCT06457828 clinical trial?
NCT06457828 is sponsored by Suez Canal University. The trial plans to enroll 40 participants.