NCT04460859 RecruitmEnt Assessed by eleCtRical Impedance Tomography
| NCT ID | NCT04460859 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Unity Health Toronto |
| Condition | Acute Respiratory Distress Syndrome (ARDS) |
| Study Type | OBSERVATIONAL |
| Enrollment | 171 participants |
| Start Date | 2020-06-09 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 171 participants in total. It began in 2020-06-09 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The RECRUIT study is a multinational, multicenter physiological observational study conducted by the PLUG working group. It is a single-day study (1.5-2 hours) associated with specific lung (de)recruitment maneuvers to verify the feasibility of measuring the potential for lung recruitment in mechanically ventilated patients with ARDS by electrical impedance tomography (EIT).
Eligibility Criteria
Inclusion Criteria: * Intubated moderate and severe ARDS according to the Berlin definition (PaO2/FiO2 ratio \<= 200 mmHg) * Under continuous sedation with or without paralysis Exclusion Criteria: * Age \<18 years * Bronchopleural fistula * Pure COPD exacerbation * Contraindication to EIT monitoring (e.g. burns, pacemaker, thoracic wounds limiting electrode belt placement) * Hemodynamic instability (Systolic BP \< 75 mmHg or MAP \< 60 mmHg despite vasopressors and/or heart rate \< 55 bpm) * Attending physician deems the transient application of high airway pressures to be unsafe
Contact & Investigator
Laurent Brochard, MD
PRINCIPAL INVESTIGATOR
Unity Health Toronto
Frequently Asked Questions
Who can join the NCT04460859 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Respiratory Distress Syndrome (ARDS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04460859 currently recruiting?
Yes, NCT04460859 is actively recruiting participants. Contact the research team at Laurent.Brochard@unityhealth.to for enrollment information.
Where is the NCT04460859 trial being conducted?
This trial is being conducted at São Paulo, Brazil, Toronto, Canada, Milan, Italy, Barcelona, Spain.
Who is sponsoring the NCT04460859 clinical trial?
NCT04460859 is sponsored by Unity Health Toronto. The principal investigator is Laurent Brochard, MD at Unity Health Toronto. The trial plans to enroll 171 participants.