Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation
Trial Parameters
Eligibility Fast-Check
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Brief Summary
This study will test the clinical efficacy of an accelerated TMS (accel-TMS) protocol that rapidly addresses PTSD symptoms with 1 week (25 sessions over 5 days) of condensed treatment.
Eligibility Criteria
Inclusion: 1. Adults age 18 years to 65 years old. 2. Meets DSM-5 criteria for PTSD with a PCL-5 score \> 33 3. No changes in psychotropic medication (if taking psychotropic medication) and/or changes in supportive psychotherapy for 1 month prior to initial visit; and clinically appropriate to maintain stable treatment regimen for duration of trial. 4. Clinically competent to give informed written consent and ability to understand study procedures and to comply with them for the entire length of the study Exclusion: 1. Medical contraindication for neuromodulation (e.g., ferrous metal in head, seizure disorder, brain tumor, stroke, aneurysm, multiple sclerosis, etc.). 2. Active substance use disorder in last 3 months or any current substance use that puts the participant at increased risk or significant impairment. 3. Dementia or other cognitive disorder making unable to engage in treatment. 4. Any history or diagnosis of Schizophrenia, Schizoaffective Disorder, Delusional Disorder or o