NCT05599022 Randomized Assessment of TcMS for VT Storm
| NCT ID | NCT05599022 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pennsylvania |
| Condition | Ventricular Tachycardia |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2023-05-22 |
| Primary Completion | 2028-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2023-05-22 with a primary completion date of 2028-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Three-arm randomized clinical trial comparing two strategies of TcMS to sham stimulation in patients with VT storm. The hypothesis of the study is that TcMS will reduce the burden of VT in the 24 hours after randomization compared to sham stimulation and that TcMS with theta burst stimulation (TBS) will be more effective at reducing VT burden than low frequency TcMS.
Eligibility Criteria
Inclusion Criteria: * ≥3 episodes of sustained VT or appropriate ICD therapies within 24 hours despite the use of at least one antiarrhythmic drug Exclusion Criteria: * Plan for catheter ablation of VT in the next 24 hours * Pregnancy * Contraindication to TcMS (i.e. implantable ventricular assist device, metal implanted in the head or neck \[except the mouth\], implanted medication pumps, cochlear implant, implanted brain stimulator, ocular implant, history of malignancy in the neck)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05599022 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Ventricular Tachycardia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05599022 currently recruiting?
Yes, NCT05599022 is actively recruiting participants. Contact the research team at timothy.markman@pennmedicine.upenn.edu for enrollment information.
Where is the NCT05599022 trial being conducted?
This trial is being conducted at Philadelphia, United States.
Who is sponsoring the NCT05599022 clinical trial?
NCT05599022 is sponsored by University of Pennsylvania. The trial plans to enroll 60 participants.