NCT07201506 Real-Time Intracardiac Echocardiography for Ventricular Arrhythmia Ablation
| NCT ID | NCT07201506 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Insel Gruppe AG, University Hospital Bern |
| Condition | Ablation of Arrhythmias |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2026-03-25 |
| Primary Completion | 2027-03-25 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2026-03-25 with a primary completion date of 2027-03-25.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is investigating whether using ultrasound directly inside the heart during ablation of heart rhythm disorders in the ventricles can reduce radiation exposure for patients. During an ablation, catheters are guided through the heart to treat the abnormal electrical signals. Usually, X-ray imaging (fluoroscopy) is used to see where the catheters are, which exposes both patients and hospital staff to radiation. The study is randomized and controlled: half of the participants will have the ablation with ultrasound inside the heart, and the other half will have the standard ablation without ultrasound during the procedure. The main goal is to compare the amount of X-ray time used during the procedure. Secondary goals are to look at safety, effectiveness, and the total procedure time. Patients with premature ventricular contractions or ventricular tachycardia can take part. A total of 70 people will be included, 35 in each group. Using ultrasound inside the heart makes it possible to see the catheters and heart structures directly, so many steps can be done without X-rays. This could make ablations safer and reduce radiation exposure. The study is being carried out at Inselspital, Bern University Hospital, and at University Hospital Basel. All steps are standardized and data are collected carefully. The results will show whether ultrasound during ablations can significantly reduce radiation and make ablations more efficient and safer.
Eligibility Criteria
Inclusion Criteria: * Patients (≥18y) undergoing a premature ventricular contraction or ventricular tachycardia ablation. Exclusion Criteria: * Origin of ventricular arrhythmia with high likelihood in the right ventricular outflow tract (left-bundle-inferior axis, \>V4 transition precordially) * Primary epicardial ablation planned * Congenital heart disease * Presence of a mechanical tricuspid valve prosthesis * Unwilling or unable to comply fully with study procedures and followup
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07201506 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Ablation of Arrhythmias. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07201506 currently recruiting?
Yes, NCT07201506 is actively recruiting participants. Contact the research team at boldizsar.kovacs@insel.ch for enrollment information.
Where is the NCT07201506 trial being conducted?
This trial is being conducted at Basel, Switzerland, Bern, Switzerland.
Who is sponsoring the NCT07201506 clinical trial?
NCT07201506 is sponsored by Insel Gruppe AG, University Hospital Bern. The trial plans to enroll 70 participants.