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Recruiting NCT05362721

PV Loop & Coarctation Study

Trial Parameters

Condition Coarctation of Aorta
Sponsor University of Minnesota
Study Type OBSERVATIONAL
Phase N/A
Enrollment 20
Sex ALL
Min Age 6 Years
Max Age N/A
Start Date 2019-06-04
Completion 2026-12-31
Interventions
Pressure-volume loop catheter

Brief Summary

Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.

Eligibility Criteria

Inclusion Criteria: * Children 6 years of age and older and adults of all races and both sexes referred for elective cardiac catheterization and stent therapy for coarctation * Those who provide informed consent for study participant. Exclusion Criteria: * Children who undergo other interventions in addition to the coarctation * Children with single ventricle physiology. * Renal impairment * Participant unwilling to sign a consent form.

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