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RecruitingNCT01644903

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

◆ AI Clinical Summary

This study tests blood, urine, and tissue samples from liver transplant recipients to see if they can help detect kidney disease, organ rejection, and hepatitis C infection early. Early detection of these conditions could help doctors provide better care and prevent serious complications after transplant.

Key Objective:The trial tests whether these samples can identify kidney disease, organ rejection, and hepatitis C earlier than current methods, potentially improving outcomes for transplant recipients.

Who to Consider:Liver transplant recipients who want to help develop better ways to monitor their health and detect complications early should consider enrolling.

Trial Parameters

ConditionLiver Transplant
SponsorNorthwestern University
Study TypeOBSERVATIONAL
PhaseN/A
Enrollment1,000
SexALL
Min Age18 Years
Max AgeN/A
Start Date2010-04
Completion2028-12

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Brief Summary

This study is being done to test blood, urine and tissue samples to see if this can help decide if CKD (Chronic Kidney Disease), AR (Acute Rejection) and HCV (Hepatitis C Virus) can be identified in its early stages. CKD damage to the kidneys, AR and HCV all lower the body's ability to function properly. Early detection of these conditions could assist with successful treatment and possibly lead to less repeat organ transplants.

Eligibility Criteria

Inclusion Criteria: 1. Male and female recipients of all races, ≥18 years of age. 2. Patients undergoing primary or subsequent living or deceased donor liver transplantation. 3. Subject and/or guardian must be able to provide informed consent. 4. Subject and/or guardian must be able to comply with the study protocol. Exclusion Criteria: 1\. Inability or unwillingness of a participant and/or guardian to provide informed consent.

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