NCT02780297 Prospective Research Rare Kidney Stones (ProRKS)
| NCT ID | NCT02780297 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | Hyperoxaluria |
| Study Type | OBSERVATIONAL |
| Enrollment | 220 participants |
| Start Date | 2016-05 |
| Primary Completion | 2028-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 220 participants in total. It began in 2016-05 with a primary completion date of 2028-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.
Eligibility Criteria
Inclusion Criteria: 1. Diagnosis of primary hyperoxaluria 2. Diagnosis of enteric hyperoxaluria 3. Diagnosis of Dent Disease 4. Diagnosis of Cystinuria 5. Diagnosis of adenine phosphoribosyltransferase deficiency (APRTd) 6. Diagnosis of Lowe Syndrome 7. Diagnosis of Dent Disease Carrier Exclusion Criteria: 1. Prior renal failure 2. History of liver and/or kidney transplant.
Contact & Investigator
John Lieske, MD
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT02780297 clinical trial?
This trial is open to participants of all sexes, studying Hyperoxaluria. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT02780297 currently recruiting?
Yes, NCT02780297 is actively recruiting participants. Contact the research team at RareKidneyStones@mayo.edu for enrollment information.
Where is the NCT02780297 trial being conducted?
This trial is being conducted at Birmingham, United States, Jacksonville, United States, Chicago, United States, Boston, United States and 7 additional locations.
Who is sponsoring the NCT02780297 clinical trial?
NCT02780297 is sponsored by Mayo Clinic. The principal investigator is John Lieske, MD at Mayo Clinic. The trial plans to enroll 220 participants.