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Recruiting NCT05983185

Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation

Trial Parameters

Condition Spatial Neglect After Right Brain Stroke
Sponsor VA Office of Research and Development
Study Type INTERVENTIONAL
Phase N/A
Enrollment 244
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-02-01
Completion 2026-12-31
Interventions
Prism adaptation therapy

Brief Summary

After a right brain stroke, \>50% of Veterans experience problems with dressing, eating, self-care or steering their wheelchairs because their ability to move, orient, and respond toward the left side is limited: spatial neglect. Spatial neglect prevents them from functioning independently, and their needs in the hospital and at home are greatly increased. An effective treatment for spatial neglect is 10 days of visuomotor training while wearing optical prisms (PAT), however many clinicians \[fail to diagnose spatial neglect and use this approach. In this study, the investigators will develop a brain scanning test that could objectively identify the Veterans with spatial neglect after stroke who are the best candidates to receive PAT and recover their ability to function. When the research is complete, the investigators expect that brain scans done in the hospital can guide the team to refer Veterans to PAT rehabilitation: improving daily life function\] and quality of life.

Eligibility Criteria

Inclusion Criteria: * Has had a first right brain stroke \>18 years of age * 1-4 months post-diagnosis of right brain stroke * Can sit up, see out of both eyes and point to objects (\>20/50 vision in both eyes) * Can give informed consent to participate Exclusion Criteria: * Has been diagnosed with other chronic, disabling neurological disorder (e.g. multiple sclerosis, Alzheimer Disease) * Has had a clinical left brain stroke or has neuroimaging evidence of prior stroke(s) including the presence of more than two lacunes with diameter greater than 15 mm. * Cannot sit up to be tested and receive PAT * Has \<20/50 vision when viewing with both eyes

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