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Recruiting NCT06640569

Preliminary Characterization of Commercial Kratom Extract Products

Trial Parameters

Condition Kratom Pharmacodynamics
Sponsor Johns Hopkins University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 16
Sex ALL
Min Age 21 Years
Max Age N/A
Start Date 2024-11-11
Completion 2027-11-11

Brief Summary

To understand the acute subjective, physiological, and cognitive effects of commercial kratom extract products among US adults who consume these products regularly, and to understand how these products are metabolized by the human body.

Eligibility Criteria

Inclusion Criteria: * 1\) \>21 years old; * 2\) Experienced kratom extract product consumer of one of the leading US brands listed in the study protocol; * 3\) Reports a specific kratom extract product brand and specific dose amount (or range of typical dose amount) on the online screener; * 4\) English language proficient; * 5\) Willingness to provide requested samples of the kratom extract product currently being taken. Exclusion Criteria: * 1\) Reports any acute adverse or unexpected or otherwise sudden health event related to their typical kratom product dose that occurred within 30 days of screening; * 2\) Having ever sought medical attention for an acute adverse health event as a result of taking any kratom product; * 3\) Cannot or will not provide their kratom extract product samples in the form of an unopened package that is clearly labeled with at least the product and vendor name; * 4)The kratom extract product used by the participant has any semi-synthetic or fully synthetic

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