| NCT ID | NCT02673996 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Calgary |
| Condition | Postural Tachycardia Syndrome |
| Study Type | OBSERVATIONAL |
| Enrollment | 125 participants |
| Start Date | 2016-01 |
| Primary Completion | 2029-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 125 participants in total. It began in 2016-01 with a primary completion date of 2029-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Objective: In this pilot study, we will test the hypothesis that patients with POTS (age 18-60 years) will have a higher percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS.
Eligibility Criteria
Inclusion Criteria: * Patients who have been previously diagnosed with POTS * Control subjects (patients not diagnosed with POTS) * Age between 18 - 60 years * Males and Females (Give that \>80% of POTS patients are female, we will attempt to enroll a similar percentage of female control subjects) * Able and willing to provide consent Exclusion Criteria: * Smokers * Overt cause for postural tachycardia, i.e., acute dehydration * Significant cardiovascular, pulmonary, hepatic, or hematological disease by history or prior testing * Highly trained athletes * Subjects with somatization or severe anxiety symptoms will be excluded * Use of drospirenone (a spironolactone analogue) containing oral contraceptive agent * Hypertension defined as supine resting BP\>145/95 mmHg off medications or needing antihypertensive medication * Other factors which in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies or an unpredictable schedule * Unable to give informed consent
Contact & Investigator
Satish R Raj, MD, MSCI
PRINCIPAL INVESTIGATOR
University of Calgary
Frequently Asked Questions
Who can join the NCT02673996 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Postural Tachycardia Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT02673996 currently recruiting?
Yes, NCT02673996 is actively recruiting participants. Contact the research team at autonomic.research@ucalgary.ca for enrollment information.
Where is the NCT02673996 trial being conducted?
This trial is being conducted at Calgary, Canada.
Who is sponsoring the NCT02673996 clinical trial?
NCT02673996 is sponsored by University of Calgary. The principal investigator is Satish R Raj, MD, MSCI at University of Calgary. The trial plans to enroll 125 participants.