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Recruiting Phase 4 NCT06251076

NCT06251076 Plan Development for Giving Teclistamab in the Outpatient Setting

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Clinical Trial Summary
NCT ID NCT06251076
Status Recruiting
Phase Phase 4
Sponsor University Health Network, Toronto
Condition Multiple Myeloma
Study Type INTERVENTIONAL
Enrollment 15 participants
Start Date 2024-11-19
Primary Completion 2026-06-15

Trial Parameters

Condition Multiple Myeloma
Sponsor University Health Network, Toronto
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 15
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-11-19
Completion 2026-06-15
Interventions
TeclistamabTocilizumab

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Brief Summary

This is a pilot study to develop an outpatient-based process for the administration of teclistamab for for relapsed/refractory multiple myeloma patients and to evaluate the burden on caregivers of patients receiving outpatient administration of teclistamab.

Eligibility Criteria

Multiple Myeloma Patients to Receive Outpatient Teclistamab (Part 1): Inclusion Criteria: 1. Eligible for teclistamab treatment as per Health Canada approved indication: 1. Age 18 and greater 2. Relapsed or refractory multiple myeloma 3. Received at least 3 prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody 4. Demonstrated disease progression on the last therapy 2. For Cohorts 1 and 2, participants must agree to receive treatment at Princess Margaret Cancer Centre. For Cohort 3, participants must agree to receive treatment at Stronach Regional Cancer Centre. 3. Must sign the informed consent form (or their legally acceptable representative must sign) indicating that the participant understands the purpose of, and procedures required for the study and is willing to participate in the study. Consent is to be obtained prior to the initiation of any study-related tests or procedures that are not part of standard of care

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