NCT07032870 Physical Therapist Inter-Rater Reliability in Neuro-Muscle Ultrasound in Critically Ill Patients
| NCT ID | NCT07032870 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Chile |
| Condition | Critical Illness |
| Study Type | OBSERVATIONAL |
| Enrollment | 37 participants |
| Start Date | 2025-02-08 |
| Primary Completion | 2025-12-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 37 participants in total. It began in 2025-02-08 with a primary completion date of 2025-12-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to evaluate the feasibility and inter-rater reliability of muscle and peripheral nerve ultrasound for the early detection of ICU-acquired weakness (ICU-AW) in critically ill patients. The main questions it aims to answer are: Can ICU physical therapists consistently measure muscle and nerve ultrasound variables such as muscle thickness, cross-sectional area, pennation angle, and echogenicity in critically ill patients? Do clinical scales (MRC-SS and FSS-ICU) show inter-evaluator agreement and correlate with ultrasound findings? Participants are adult ICU patients at Clínica INDISA who are undergoing routine neuromuscular assessments by trained physical therapists. Each patient will be evaluated by three independent raters using ultrasound and standardized clinical scales. Data will be collected and analyzed to determine inter-rater reliability and correlations between clinical and imaging findings.
Eligibility Criteria
Inclusion Criteria: * Adult patients (≥18 years old) admitted to the Adult Intensive Care Unit (ICU) of Clínica INDISA. * Conscious and clinically stable at the time of assessment. * Able to provide written informed consent. Exclusion Criteria: * Known allergy to ultrasound gel. * Body mass index (BMI) ≥ 30 kg/m². * Pre-existing neuromuscular disease. * Continuous renal replacement therapy or severe hepatic coagulopathy. * Platelet count \< 20,000/µL. * Lower limb amputation or recent fractures. * Ongoing chemotherapy or immunosuppressive treatment with corticosteroids. * Epileptic status or pregnancy.
Contact & Investigator
Paola A Llanos, PhD
STUDY CHAIR
University of Chile
Frequently Asked Questions
Who can join the NCT07032870 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Critical Illness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07032870 currently recruiting?
Yes, NCT07032870 is actively recruiting participants. Contact the research team at oscar.arellano@ug.uchile.cl for enrollment information.
Where is the NCT07032870 trial being conducted?
This trial is being conducted at Santiago, Chile.
Who is sponsoring the NCT07032870 clinical trial?
NCT07032870 is sponsored by University of Chile. The principal investigator is Paola A Llanos, PhD at University of Chile. The trial plans to enroll 37 participants.