NCT05994014 PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
| NCT ID | NCT05994014 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Johns Hopkins University |
| Condition | Coronary Artery Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 33 participants |
| Start Date | 2023-07-01 |
| Primary Completion | 2026-06 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 33 participants in total. It began in 2023-07-01 with a primary completion date of 2026-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Early detection of coronary atherosclerotic disease facilitates adequate prevention. The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography / computed tomography (NaF-PET/CT) with those of conventional and ultra-high-resolution-CT (UHR-CT) in patients with suspected coronary artery disease. For this purpose, the investigators plan to include 33 patients with symptoms concerning for CAD who have been referred for cardiac CT testing.
Eligibility Criteria
Inclusion Criteria: * Male or female patients * 18 years or older * referred for coronary CT angiography because of suspected coronary heart disease (CHD) with stable symptoms Exclusion Criteria: * The patient has a history of coronary heart disease, defined by prior myocardial infarction or prior coronary artery revascularization. * Pregnancy. * Atrial fibrillation. * Morbid obesity defines as a body mass index of \>40. * The patient has any other clinically significant medical condition that in the opinion of the Investigator could impact the patient's ability to successfully complete the trial.
Contact & Investigator
Armin Zadeh, MD PhD MPH
PRINCIPAL INVESTIGATOR
Johns Hopkins School of Medicine
Frequently Asked Questions
Who can join the NCT05994014 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Coronary Artery Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05994014 currently recruiting?
Yes, NCT05994014 is actively recruiting participants. Contact the research team at azadeh1@jhmi.edu for enrollment information.
Where is the NCT05994014 trial being conducted?
This trial is being conducted at Baltimore, United States.
Who is sponsoring the NCT05994014 clinical trial?
NCT05994014 is sponsored by Johns Hopkins University. The principal investigator is Armin Zadeh, MD PhD MPH at Johns Hopkins School of Medicine. The trial plans to enroll 33 participants.