NCT07929090 Pectoral Nerve Block Versus Serratus Posterior Superior Intercostal Plane Block for Pain Control After Mastectomy
| NCT ID | NCT07929090 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bursa City Hospital |
| Condition | Postoperative Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 78 participants |
| Start Date | 2026-11-01 |
| Primary Completion | 2027-06-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 78 participants in total. It began in 2026-11-01 with a primary completion date of 2027-06-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study compares two ultrasound-guided nerve block techniques for pain control after mastectomy for breast cancer: the pectoral nerve block (PECS II) and the serratus posterior superior intercostal plane (SPSIP) block. Both techniques involve injecting local anesthetic near nerves supplying the surgical area. The study will include 78 adults aged 18 to 85 years undergoing elective mastectomy under general anesthesia. Participants will be randomly assigned to receive one of the two blocks before surgery. Both groups will receive postoperative pain treatment, including a patient-controlled device that delivers tramadol when needed. The main aim is to compare postoperative opioid consumption. The study will also assess pain at rest and during movement, the need for additional pain medication, side effects, recovery quality, and persistent pain. Pain scores and tramadol consumption will be recorded at 0, 2, 4, 8, 16, and 24 hours after surgery. Recovery quality will be assessed at 24 hours, and persistent pain will be assessed by telephone at 3 months.
Eligibility Criteria
Inclusion Criteria: * Age between 18 and 85 years. * Scheduled for elective mastectomy for breast cancer under general anesthesia. * American Society of Anesthesiologists (ASA) physical status I, II, or III. * Willingness to participate in the study and provide informed consent. Exclusion Criteria: * Refusal to participate in the study. * History of bleeding diathesis or coagulopathy. * Receiving anticoagulant therapy. * Allergy or hypersensitivity to local anesthetics or opioid medications. * History of local anesthetic toxicity. * Infection at the planned block injection site. * Hepatic or renal failure. * Uncontrolled diabetes mellitus. * Uncontrolled hypertension. * Intellectual disability. * Receiving opioid treatment for chronic pain. * Pregnancy, suspected pregnancy, or breastfeeding. * Planned bilateral mastectomy.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07929090 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 85 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07929090 currently recruiting?
Yes, NCT07929090 is actively recruiting participants. Contact the research team at enbatuca55@gmail.com for enrollment information.
Where is the NCT07929090 trial being conducted?
This trial is being conducted at Nilufer, Turkey (Türkiye).
Who is sponsoring the NCT07929090 clinical trial?
NCT07929090 is sponsored by Bursa City Hospital. The trial plans to enroll 78 participants.