NCT06725160 Parent Encouragement And Coaching of Happiness in Youth
| NCT ID | NCT06725160 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pittsburgh |
| Condition | Depression |
| Study Type | INTERVENTIONAL |
| Enrollment | 180 participants |
| Start Date | 2025-10-28 |
| Primary Completion | 2029-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 180 participants in total. It began in 2025-10-28 with a primary completion date of 2029-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1. Characterize child neural reward response and its relation to maternal socialization of positive emotions at baseline in healthy young children. Aim 2. Evaluate how coaching-related changes in maternal socialization of positive emotion expression contribute to increases in child neural reward response over time. Aim 3. Examine how maternal socialization of positive emotion expression contributes to increases in child neural reward response in the moment. Participating mother-child dyads will be randomized to either 3 sessions of parent coaching of child positive affect or 3 sessions of a general parenting support intervention and neural response to reward and affective behavior will be examined pre and post intervention.
Eligibility Criteria
Inclusion Criteria for Mothers: * Birth mother (biologically female, any gender) * Providing regular care for participating child (i.e., at least 50% of time) * Elevated, clinically significant levels of depression (16 or higher on CES-D) * Aged 18+ Exclusion Criteria for Mothers: * Lifetime history of a bipolar disorder * Lifetime history of a psychotic disorder Inclusion Criteria for Participating Child: -Aged 4-6 years Exclusion Criteria for Participating Child: * T-score greater than 63 on the internalizing or externalizing composites of the CBCL * Lifetime history of a psychiatric illness * Lifetime history of neurodevelopmental disorder * Lifetime history of neurological disorder
Contact & Investigator
Judith M Morgan, PhD
PRINCIPAL INVESTIGATOR
University of Pittsburgh
Frequently Asked Questions
Who can join the NCT06725160 clinical trial?
This trial is open to participants of all sexes, aged 4 Years or older, up to 99 Years, studying Depression. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06725160 currently recruiting?
Yes, NCT06725160 is actively recruiting participants. Contact the research team at PEACHY@upmc.edu for enrollment information.
Where is the NCT06725160 trial being conducted?
This trial is being conducted at Pittsburgh, United States.
Who is sponsoring the NCT06725160 clinical trial?
NCT06725160 is sponsored by University of Pittsburgh. The principal investigator is Judith M Morgan, PhD at University of Pittsburgh. The trial plans to enroll 180 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.