NCT06508502 Pancreatitis - Microbiome as Predictor of Severity II
| NCT ID | NCT06508502 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Medical Center Goettingen |
| Condition | Acute Pancreatitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 700 participants |
| Start Date | 2024-05-01 |
| Primary Completion | 2027-05-01 |
Trial Parameters
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Brief Summary
The goal of this observational study is to evaluate the orointestinal microbiome and microbial derived metabolome in patients suffering from acute pancreatitis as a biomarker for severity. The main questions it aims to answer are: * Can the orointestinal microbiome robustly predict the course of acute pancreatitis? * How does the microbiome impact the severity of an acute pancreatitis? Buccal/ rectal swabs, plasma and stool is collected from patients with acute pancreatitis within 48h after hospital admission.
Eligibility Criteria
Inclusion Criteria: * Patients with initial diagnosis (\< 48h) of acute pancreatitis * Age ≥ 18 years * Patients able to understand/ give their written consent Exclusion Criteria: * Recurrent acute pancreatitis (\>2 previous episodes) * Clinical or imaging signs of chronic pancreatitis * Referred patients with length of hospital stay \> 48h