NCT05748028 Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms
| NCT ID | NCT05748028 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Istituti Clinici Scientifici Maugeri SpA |
| Condition | Parkinson Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 280 participants |
| Start Date | 2019-06-15 |
| Primary Completion | 2026-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 280 participants in total. It began in 2019-06-15 with a primary completion date of 2026-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers. The main aims are: Evaluate the prevalence of pain and characterize it in Parkinson's disease and atypical parkinsonisms (MSA) Evaluate the effect of rehabilitation on pain and autonomic symptoms Evaluate the prevalence of autonomic symptoms in Parkinson's disease and atypical parkinsonisms (MSA) Assess the impact of pain and autonomic symptoms on quality of life. Participants will perform neurological examination, rehabilitation program and clinical scales. Researchers will compare the two groups of patients (PD and MSA) and the effect of the rehabilitation on pain, autonomic symptoms and quality of life.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of Parkinson's Disease or Multiple System Atrophy according to current international criteria (Gilman S et al, 2008; Postuma RB et al. 2015). * Mini-Mental State Examination score at least 10 Exclusion Criteria: * vascular or pharmacological parkinsonism * diabetes mellitus * hepatic or renal dysmetabolism, * hypothyroidism or hyperthyroidism * assumption of potentially neurotoxic drugs
Contact & Investigator
Maria Nolano, MD, PhD
PRINCIPAL INVESTIGATOR
Isituti Clinici Scientifici Maugeri SpA SB - IRCCS of Telese Terme
Frequently Asked Questions
Who can join the NCT05748028 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Parkinson Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05748028 currently recruiting?
Yes, NCT05748028 is actively recruiting participants. Contact the research team at maria.nolano@icsmaugeri.it for enrollment information.
Where is the NCT05748028 trial being conducted?
This trial is being conducted at Telese Terme, Italy, Lumezzane, Italy, Castel Goffredo, Italy, Mistretta, Italy and 5 additional locations.
Who is sponsoring the NCT05748028 clinical trial?
NCT05748028 is sponsored by Istituti Clinici Scientifici Maugeri SpA. The principal investigator is Maria Nolano, MD, PhD at Isituti Clinici Scientifici Maugeri SpA SB - IRCCS of Telese Terme. The trial plans to enroll 280 participants.
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