NCT04113070 Overweight and Obesity and Puberty Development Cohort Study
| NCT ID | NCT04113070 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai Jiao Tong University School of Medicine |
| Condition | Precocious Puberty |
| Study Type | OBSERVATIONAL |
| Enrollment | 14,100 participants |
| Start Date | 2019-10-11 |
| Primary Completion | 2026-10-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 14,100 participants in total. It began in 2019-10-11 with a primary completion date of 2026-10-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Precocious puberty and childhood overweight and obesity are important public health problems that both had adverse effects, which including psychological symptom in childhood, short final height or reproductive dysfunction in adulthood, on children's physical and psychological development.The prevalence of precocious puberty and childhood overweight and obesity are both high, and a growing body of epidemiological studies suggested that there was a close relationship of childhood overweight and obesity with puberty development, especially in girls. However, the underlying mechanism between them is unclear. Existing evidence shows that the occurrence of precocious puberty and overweight and obesity are the result of interaction of multiple factors, which consists growth environment and genetics, and many previous studies provided that more overlapping genes existed between obesity and precocious puberty patients, suggesting that common genes may result in these diseases. Therefore, based on a case control study, which will investigate the associations between obesity pleiotropic genes and early puberty, the researchers will collect information related to obesity, growth environment factors and risk genes in this study to evaluate the relationships of these related factors and precocious puberty, and to further explore whether there exists biological interaction effects of these risk factors on sexual precocity. This project has been approved by the Ethics Committee of Shanghai Children's Medical Center.
Eligibility Criteria
Inclusion Criteria: * Children over 6 years old from grade 1, 2 and 3 in selected primary schools in Zhongshan, Qufu and Huhhot since 2019 Exclusion Criteria: * Children with overweight or obesity had a history of hormone drug treatment last for 6 months
Contact & Investigator
Shijian Liu, Ph.D
PRINCIPAL INVESTIGATOR
Shanghai Children's Medical Center
Frequently Asked Questions
Who can join the NCT04113070 clinical trial?
This trial is open to participants of all sexes, aged 6 Years or older, up to 12 Years, studying Precocious Puberty. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04113070 currently recruiting?
Yes, NCT04113070 is actively recruiting participants. Contact the research team at liushijian@scmc.com.cn for enrollment information.
Where is the NCT04113070 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT04113070 clinical trial?
NCT04113070 is sponsored by Shanghai Jiao Tong University School of Medicine. The principal investigator is Shijian Liu, Ph.D at Shanghai Children's Medical Center. The trial plans to enroll 14,100 participants.