This study investigates how different types of blood flow during heart surgery affect organ function after the procedure. Cardiopulmonary bypass machines pump blood during surgery, but researchers want to determine whether pulsating (wave-like) blood flow is better than steady flow for protecting organs from damage.
Key Objective:The trial is testing whether pulsatile blood flow during cardiopulmonary bypass can reduce organ damage and improve recovery after cardiac surgery.
Who to Consider:Patients scheduled to undergo cardiac surgery who are interested in potentially optimizing their surgical blood flow management should consider enrolling.
Trial Parameters
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Brief Summary
Cardiopulmonary bypass during cardiac surgery provides blood flow to the body during surgery but has adverse effects on different organs. Blood flow during cardiopulmonary bypass may be pulsatile or non-pulsatile, which may impact normal organ function after surgery. The study will collect data on the type of cardiopulmonary bypass used during surgery and organ function to determine if there is an association between the type of bypass and organ function.
Eligibility Criteria
Inclusion Criteria: * Age 50 to 70 * Able to provide informed consent * Scheduled for elective cardiac surgery with cardiopulmonary bypass Exclusion Criteria: * Patients undergoing emergency procedures * Diagnosed with sepsis * Experiencing delirium * Experiencing hemodynamic instability (heart rate \> 100 and systolic blood pressure \< 90) * Patients with a mechanical circulatory support device * Requiring vasoactive medications before surgery * Patients with a reduced left ventricular ejection fraction (less than 50%) * Patients with a contraindication to transesophageal echocardiography