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acute kidney injury

Total Trials
20
Recruiting Now
20
Trial Phases
Phase 2, Phase 1, Phase 2, Phase 4

ClinicalMetric tracks all active clinical trials for acute kidney injury sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — acute kidney injury Clinical Trials

How many clinical trials are currently recruiting for acute kidney injury?
ClinicalMetric currently tracks 20 actively recruiting clinical trials for acute kidney injury, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 20. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for acute kidney injury?
acute kidney injury research spans Phase 1 (2 trials), Phase 2 (5 trials), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a acute kidney injury clinical trial?
Eligibility criteria for acute kidney injury trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
2
Phase 2
5
Phase 3
1
Phase 4
1
Top Sponsors
Xijing Hospital 1 trial
Peking University First Hospital 1 trial
The Hospital for Sick Children 1 trial
Insel Gruppe AG, University Hospital Bern 1 trial
Post Graduate Institute of Medical Education and Research, Chandigarh 1 trial

Recruiting Clinical Trials

NCT06248359
Recruiting
Association Between Postoperative Administration of L-Arginine and CSA-AKI
Enrollment
7,000 pts
Location
China
Sponsor
Xijing Hospital
View Trial →
NCT07088874
Recruiting
Novel Biomarkers and Postoperative Kidney Injury in Radical Nephrectomy
Enrollment
60 pts
Location
China
Sponsor
Peking University First Hospit...
View Trial →
NCT04442516
Recruiting
Cisplatin Induced Kidney Toxicity
Enrollment
600 pts
Location
Canada
Sponsor
The Hospital for Sick Children
View Trial →
NCT06471621
Recruiting
Precision Medicine in Cardiovascular Surgery Associated Acute Kidney Injury
Enrollment
100 pts
Location
Switzerland
Sponsor
Insel Gruppe AG, University Ho...
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NCT06431919
Recruiting
Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival
Enrollment
260 pts
Location
India
Sponsor
Post Graduate Institute of Med...
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NCT07052513 Phase 2
Recruiting
Modified Autologous Leukocyte Cells for the Treatment of Acute Kidney Injury After Cardiac Surgery
Enrollment
98 pts
Location
Spain
Sponsor
M2RLAB SL
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NCT03720860
Recruiting
Inflammatory Mediators of Acute Kidney Injury in Intensive Care
Enrollment
100 pts
Location
Sweden
Sponsor
Uppsala University
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NCT06886464 Phase 2
Recruiting
Prevention of Nephrotoxin-Induced Acute Kidney Injury Using Cilastatin
Enrollment
698 pts
Location
Canada
Sponsor
Matthew James
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NCT06349577
Recruiting
Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury
Enrollment
1,100 pts
Location
United States
Sponsor
University of Colorado, Denver
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NCT07258875
Recruiting
Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
Enrollment
230 pts
Location
Greece
Sponsor
University of Crete
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NCT06654193 Phase 1, Phase 2
Recruiting
Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury
Enrollment
70 pts
Location
United States
Sponsor
Hope Biosciences LLC
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NCT06032884
Recruiting
IHD Versus CRRT for Severe Acute Kidney Injury in Critically Ill Patients
Enrollment
1,000 pts
Location
France
Sponsor
Assistance Publique - Hôpitaux...
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NCT06570187 Phase 4
Recruiting
The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients
Enrollment
128 pts
Location
Egypt
Sponsor
Cairo University
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NCT07236463 Phase 1, Phase 2
Recruiting
Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury
Enrollment
14 pts
Location
France
Sponsor
Centre Hospitalier Universitai...
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NCT04722939
Recruiting
Neurocognitive Outcomes for ICU Patients With Acute Kidney Injury
Enrollment
104 pts
Location
Canada
Sponsor
Dr. Gordon Boyd
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NCT05817929
Recruiting
Angiopoietin and Adverse Outcomes in Cardiac Surgery
Enrollment
200 pts
Location
France
Sponsor
Centre Hospitalier Universitai...
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NCT06537453
Recruiting
UPTAKE - Virtual Care: Virtual Home Hospital With Remote Monitoring to Reduce Acute Care Hospitalization
Enrollment
354 pts
Location
Canada
Sponsor
University of Calgary
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NCT05346393
Recruiting
HRS-AKI Treatment With TIPS in Patients With Cirrhosis
Enrollment
124 pts
Location
Germany
Sponsor
Jena University Hospital
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NCT06937307 Phase 2
Recruiting
Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury
Enrollment
75 pts
Location
United States
Sponsor
Giuseppe Cullaro, MD
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NCT05906758 Phase 3
Recruiting
Ultra-Low Contrast Angiography in AKI
Enrollment
32 pts
Location
United States
Sponsor
Tulane University
View Trial →

Related Conditions

sepsis (3) cirrhosis liver (2) surgery (2) nephrectomy (1) biomarker (1) cancer (1) surgery complications (1) frailty (1) decompensated cirrhosis (1) cirrhotic cardiomyopathy (1) left ventricular diastolic dysfunction (1) hemolysis (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology