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Medical Condition

acute kidney injury

Total Trials

20

Recruiting Now

20

Trial Phases

Phase 4, Phase 2, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for acute kidney injury sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — acute kidney injury Clinical Trials

How many clinical trials are currently recruiting for acute kidney injury?

ClinicalMetric currently tracks 20 actively recruiting clinical trials for acute kidney injury, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 20. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for acute kidney injury?

acute kidney injury research spans Phase 2 (4 trials), Phase 3 (2 trials), Phase 4 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a acute kidney injury clinical trial?

Eligibility criteria for acute kidney injury trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

4

Phase 3

2

Phase 4

3

Top Sponsors

Chiang Mai University 1 trial

University of Alabama at Birmingham 1 trial

AstraZeneca 1 trial

University of California, San Francisco 1 trial

The University of Texas Health Science Center, Houston 1 trial

Recruiting Clinical Trials

NCT06229990 Phase 4

Effect of a Furosemide Stress Test-Guided Strategy on Liberation From Continuous Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury

Chiang Mai University

The Biosonographic Index

University of Alabama at Birmi...

NCT07215702 Phase 2

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

United States, Argen...

NCT07734636 Phase 4

A Prompt REstart Study of Renin-Angiotensin System Inhibitors After Acute Kidney Injury

University of California, San ...

NCT06531642 Phase 2, Phase 3

Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients

The University of Texas Health...

UPTAKE: Using Personalized Risk and Digital Tools to Guide Transitions Following Acute Kidney Events

University of Alberta

Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine

University Medical Center Gron...

UPTAKE - Virtual Care: Virtual Home Hospital With Remote Monitoring to Reduce Acute Care Hospitalization

University of Calgary

Initial Resuscitation for Acute Kidney Injury in Cirrhosis

Massachusetts General Hospital

NCT05084196 Phase 3

Melatonin for Prevention of Kidney Injury

Rutgers, The State University ...

Cystatin and Early AKI Detection Contrast Induced Acute Kidney Injury

BayCare Health System

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

NCT07052513 Phase 2

Modified Autologous Leukocyte Cells for the Treatment of Acute Kidney Injury After Cardiac Surgery

The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICU

Peking University Third Hospit...

Perioperative Transcutaneous Fluorescence Detection of GFR Trajectory for the Early Prediction and Diagnosis of CSA-AKI.

China National Center for Card...

Standard Dose Continuous Renal Replacement Therapy (CRRT) Versus Low-Dose CRRT ( KETZEREI )

Universität Münster

NCT06570187 Phase 4

The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients

Cairo University

Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery

Onassis Cardiac Surgery Centre

NCT06954740 Phase 2

Clinical Study to Evaluate the Efficacy and Safety of Mesenchymal Stromal Cells (Amimestrocel ) in Patients With Acute Kidney Injury

Chinese PLA General Hospital

Early Deresuscitation Strategy Driven by Tissue Perfusion in Renal Replacement Therapy in Patients With Acute Renal Failure

Hospices Civils de Lyon

Related Conditions

sepsis (3) acute disease (1) pneumonia (1) frailty (1) complication of treatment (1) pulmonary embolism (1) thrombosis (1) electrolyte disturbance (1) hemorrhage (1) shock (1) polypharmacy (1) intoxication by drug (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology