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Recruiting NCT05120492

Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial

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Trial Parameters

Condition Knee Osteoarthritis
Sponsor Nova Scotia Health Authority
Study Type INTERVENTIONAL
Phase N/A
Enrollment 20
Sex ALL
Min Age 18 Years
Max Age 65 Years
Start Date 2022-04-22
Completion 2027-07
Interventions
bariatric surgery followed by total knee replacement

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Brief Summary

Does weight loss surgery in patients with morbid obesity prior to knee replacement surgery improve outcomes from knee replacement surgery

Eligibility Criteria

Inclusion Criteria: severe knee osteoarthritis body-mass index of 45 to 60 Exclusion Criteria: previous total replacement of the same knee, a need for bilateral total knee replacement, and knee pain during the previous week that the patient rated at higher than 60 mm on a 100-mm visual-analogue scale. Also,prior bariatric or complex foregut surgery, significant cardiovascular, pulmonary, renal, liver, gastrointestinal, psychiatric disorders, pregnancy, malignancy within last 5 years, anemia, coagulopathy requiring anti-coagulation therapy.

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VIEW ON CLINICALTRIALS.GOV ↗ MORE KNEE OSTEOARTHRITIS TRIALS
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